A presumptive latex agglutination test for the direct qualitative detection of antigens to H. influenzae type b, S. pneumoniae, Group B streptococcus, N. meningitidis Groups A, B, C, Y or W135, and Escherichia coli K1 in cerebrospinal fluid (CSF), serum, urine or blood culture media. In addition, the test kit provides confirmation and serogrouping capabilities from suspected colonies of H. influenzae type b, S. pneumoniae, Group B streptococcus, and N. meningitidis Groups A/Y, B or C/W135. 30 patient tests, 60 controls – 90 determinations.